
Berberine-500
by Thorne Research
Key Benefits
- Supports healthy blood sugar metabolism
- Promotes healthy cholesterol levels
- Supports cardiovascular health
- Supports healthy gut flora
💰Pricing
Product Overview
Thorne Berberine-500 Overview
Thorne's Berberine-500 offers a potent dose of berberine hydrochloride (HCl) in each capsule. Berberine is a natural plant extract with a long history of use in traditional medicine, prized for its potential to support healthy blood sugar, cardiovascular function, and gut health.
- What is Berberine? It's an alkaloid compound found in several plants, including goldenseal, barberry, and Oregon grape.
- Who should consider taking Berberine-500? Individuals looking to maintain healthy blood sugar levels, support cholesterol management, and promote gut flora balance may find this supplement beneficial. However, always consult with a healthcare professional before starting any new supplement regimen.
This product is manufactured by Thorne Research, a brand known for its commitment to quality and rigorous testing. Berberine-500 is NSF Certified for Sport, ensuring its safety and purity for athletes and individuals concerned about banned substances.

How It Works
Berberine's mechanism of action involves multiple pathways within the body. It primarily works by activating an enzyme called AMPK (adenosine monophosphate-activated protein kinase), which plays a crucial role in regulating energy metabolism. AMPK activation can improve insulin sensitivity, promote glucose uptake by cells, and reduce glucose production in the liver. Berberine also influences gut microbiota composition, potentially contributing to improved digestion and metabolic health. Additionally, it may help regulate cholesterol levels by affecting lipid metabolism and reducing LDL cholesterol (bad cholesterol).

Benefits & Research
Benefits of Thorne Berberine-500
- Supports healthy blood sugar levels already within a normal range.
- Promotes healthy cholesterol levels.
- Supports cardiovascular health by promoting healthy blood vessel function.
- May aid in weight management by supporting healthy metabolism.
- Supports healthy gut flora and digestion.
- Potentially reduces fatigue
- May increase energy levels
- May assist with improved mood and reduced stress
- May aid with a boosted immune system

Potential Side Effects
While Berberine-500 is generally well-tolerated, some individuals may experience mild side effects, particularly gastrointestinal discomfort, such as nausea, diarrhea, or stomach cramps. These side effects are usually temporary and subside with continued use. It's important to start with a lower dose and gradually increase it to assess tolerance. Consult your physician if you have concerns.

Frequently Asked Questions
How should I take Thorne Berberine-500?
The recommended dosage is 1 capsule twice daily with meals. It's best to spread the doses throughout the day for optimal absorption and to minimize potential side effects.
Can I take Berberine-500 with other supplements?
Berberine-500 can generally be taken with other supplements. However, it's always a good idea to consult with your healthcare provider to ensure there are no potential interactions.
Is Berberine-500 safe for pregnant or breastfeeding women?
No. Berberine is not recommended for pregnant or breastfeeding women due to potential risks to the fetus or infant. Consult with your doctor for more information.
How long does it take to see results from Berberine-500?
Individual results may vary. Some people may notice improvements in blood sugar levels within a few weeks, while others may require several months to experience significant benefits. Consistency is key.
Does Berberine-500 have any interactions with medications?
Berberine may interact with certain medications, including blood thinners, diabetes medications, and some antibiotics. Always consult with your doctor before taking berberine if you are taking any prescription medications.
Is Berberine-500 suitable for vegans and vegetarians?
Yes, Berberine-500 is suitable for vegans and vegetarians as it contains no animal-derived ingredients.
Does this need to be refrigerated?
No, but it's recommended to store it in a cool, dark, and dry place.
Detailed Scores & Effectiveness
Product Scores
Effectiveness by Goal
Customer Reviews (6)
Great for Blood Sugar
This berberine supplement has helped me maintain healthy blood sugar levels. I've noticed a difference since I started taking it.
Good Product, Slight GI Issues
I experienced mild stomach upset initially, but it subsided after a few days. The product seems to be working as intended.
Effective and Well-Tolerated
I've been using this berberine for a month, and I'm very happy with the results. No side effects, and my blood sugar readings are better.
Okay, I didn't notice much difference
It could be that I don't have any existing health issues related to blood sugar but after a month of taking it twice a day I didn't notice much difference.
Great product, easy to swallow
These capsules are easy to swallow and I really enjoy them.
Definitely helped me
I used to have much higher blood sugar levels, I think this helped improve it after taking it consistently for 2 months.
Product Specs
Key Ingredients
Berberine HCl
Grade AHypromellose
Grade N/AMicrocrystalline Cellulose
Grade N/ACalcium Laurate
Grade N/ASilicon Dioxide
Grade N/ACertifications
Important Warnings
- • If pregnant, consult your health professional before using this product.
- • May cause mild gastrointestinal discomfort in some individuals.
- • Consult with a doctor if you are taking prescription medications, especially blood thinners or medications for diabetes.